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Papers of the Week


Papers: 11 Jul 2020 - 17 Jul 2020


Human Studies, Pharmacology/Drug Development


2020 Jul 15


BMC Med


18


1

All-cause mortality in patients with long-term opioid therapy compared with non-opioid analgesics for chronic non-cancer pain: a database study.

Authors

Häuser W, Schubert T, Vogelmann T, Maier C, Fitzcharles M-A, Tölle T
BMC Med. 2020 Jul 15; 18(1):162.
PMID: 32664901.

Abstract

Hitherto only studies with selected populations have found an increased all-cause mortality of some selected opioids compared to selected non-opioids for chronic non-cancer pain (CNCP). We have examined the all-cause mortality for CNCP associated with all established opioids compared to non-opioid analgesic therapy (anticonvulsants, antidepressants, dipyrone, non-steroidal agents).