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Papers of the Week


Papers: 27 Jun 2020 - 3 Jul 2020


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2020 Jun 25


J Pharm Pharmacol

A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine.

Authors

von Mentzer B, Russo AF, Zhongming Z, Kuburas A, Killoran PM, D'Aloisio V, Nizic L, Capel V, Kendall DA, Coxon CR, Hutcheon GA
J Pharm Pharmacol. 2020 Jun 25.
PMID: 32588458.

Abstract

To investigate the formulation of the peptide-based antagonist ( Pro, Phe)CGRP , of the human calcitonin gene-related peptide (CGRP) receptor as a potential nasally delivered migraine treatment.