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Papers: 20 Jun 2020 - 26 Jun 2020
Animal Studies, Pharmacology/Drug Development
2020 Jun 24
Br J Pharmacol
Glutamate and metabotropic glutamate receptors on primary sensory neurons play a pivotal role in modulating pain sensitivity. However, it is unclear how inflammation affects mGluR-mediated nociceptive responses. We therefore investigated the effects of mGluR1/5 agonists on pain-related behavior under persistent inflammation and explored the underlying mechanisms.