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Papers of the Week


Papers: 23 May 2020 - 29 May 2020


Human Studies


2020 May 27


Breast Cancer Res Treat

Sensory profiles in women with neuropathic pain after breast cancer surgery.

Authors

Mustonen L, Vollert J, Rice ASC, Kalso E, Harno H
Breast Cancer Res Treat. 2020 May 27.
PMID: 32458104.

Abstract

We performed a detailed analysis of sensory function in patients with chronic post-surgical neuropathic pain (NP) after breast cancer treatments by quantitative sensory testing (QST) with DFNS (German Research Network on Neuropathic Pain) protocol and bed side examination (BE). The nature of sensory changes in peripheral NP may reflect distinct pathophysiological backgrounds that can guide the treatment choices. NP with sensory gain (i.e., hyperesthesia, hyperalgesia, allodynia) has been shown to respond to Na-channel blockers (e.g., oxcarbazepine).