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Papers of the Week
Aberrant Thalamic-Centered Functional Connectivity in Patients with Persistent Somatoform Pain Disorder.
Abstract
Recent task-based fMRI studies have shown that Persistent Somatoform Pain Disorder (PSPD) patients demonstrated aberrant activity in a wide range of brain regions associated with sensation, cognition and emotion. However, these specific task-based studies could not clearly uncover the alterations in the spontaneous brain networks that were associated with the general pain-related symptoms in PSPD.