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Papers of the Week


Papers: 15 Feb 2020 - 21 Feb 2020


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Itch


2020 Feb 20


N Engl J Med


382


8

Editor's Pick

Trial of Nemolizumab in Moderate-to-Severe Prurigo Nodularis.

Authors

Ständer S, Yosipovitch G, Legat FJ, Lacour J-P, Paul C, Narbutt J, Bieber T, Misery L, Wollenberg A, Reich A, Ahmad F, Piketty C
N Engl J Med. 2020 Feb 20; 382(8):706-716.
PMID: 32074418.

Abstract

Prurigo nodularis is a chronic pruritic skin disease with multiple nodular skin lesions. Nemolizumab is a monoclonal antibody targeting the interleukin-31 receptor, which is involved in the pathogenesis of prurigo nodularis.