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Papers of the Week


Papers: 8 Feb 2020 - 14 Feb 2020


Human Studies

PAIN TYPE:
Migraine/Headache


2020 Feb 06


Neurology

Noninvasive vagus nerve stimulation and the trigeminal autonomic reflex: An fMRI study.

Authors

Möller M, Mehnert J, Schroeder CF, May A
Neurology. 2020 Feb 06.
PMID: 32029547.

Abstract

The trigeminal autonomic reflex is a physiologic reflex that plays a crucial role in primary headache and particularly in trigeminal autonomic cephalalgias, such as cluster headache. Previous studies have shown that this reflex can be modulated by the vagus nerve, leading to an inhibition of the parasympathetic output of the reflex in healthy participants. The aim of the present study was to characterize neural correlates of the modulatory effect of noninvasive vagus nerve stimulation (nVNS) on the trigeminal autonomic reflex.