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Papers of the Week


Papers: 1 Feb 2020 - 7 Feb 2020


Animal Studies


2020 04 01


J Neurosci Methods


335

Controllable Forces for Reproducible Chronic Constriction Injury Mimicking Compressive Neuropathy in Rat Sciatic Nerve.

Authors

Chen S-H, Huang T-C, Wang J-Y, Wu C-C, Hsueh Y-Y
J Neurosci Methods. 2020 04 01; 335:108615.
PMID: 32006536.

Abstract

Compressive neuropathy is a recurring and challenging disease for patients, regardless of medical or surgical treatment. Neuropathological severity is associated with the force of mechanical compression. Available animal models do not address mechanical issues with reproducible outcomes. We used a chronic constriction injury model to analyze tension-controlled compressive neuropathy and achieve reproducible functional outcomes.