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Papers of the Week


Papers: 4 Jan 2020 - 10 Jan 2020


Pharmacology/Drug Development


2020 04


BJU Int


125


4

Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome: a Cochrane systematic review.

Authors

Franco J V, Turk T, Jung J H, Xiao Y-T, Iakhno S, Tirapegui F I, Garrote V, Vietto V
BJU Int. 2020 04; 125(4):490-496.
PMID: 31899937.

Abstract

To assess the effects of pharmacological therapies for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) PATIENTS AND METHODS: We performed a comprehensive search using multiple databases, trial registries, grey literature and conference proceedings with no restrictions on the language of publication or publication status. The date of the latest search of all databases was July 2019. We included randomised controlled trials. Inclusion criteria were men with a diagnosis of CP/CPPS. We included all available pharmacological interventions. Two review authors independently classified studies and abstracted data from the included studies, performed statistical analyses and rated quality of evidence (QoE) according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methods. The primary outcomes were prostatitis symptoms and adverse events. The secondary outcomes were sexual dysfunction, urinary symptoms, quality of life, anxiety and depression.