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Papers of the Week
Intrathecal injection of bone marrow stromal cells attenuates neuropathic pain via inhibition of P2XR in spinal cord microglia.
Abstract
Neuropathic pain is one of the most debilitating of all chronic pain syndromes. Intrathecal (i.t.) bone marrow stromal cell (BMSC) injections have a favorable safety profile; however, results have been inconsistent, and complete understanding of how BMSCs affect neuropathic pain remains elusive.