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Papers of the Week


Papers: 16 Nov 2019 - 22 Nov 2019


Human Studies


2020 Feb


Muscle Nerve


61


2

Diagnostic utility of small fiber analysis in skin biopsies from children with chronic pain.

Authors

Görlach J, Amsel D, Kölbel H, Grzybowsky M, Rutsch F, Schlierbach H, Vanlander A, Pogatzki-Zahn E, Habig K, Garkisch S, Müller V, Fritz T, Ziegler A, Hahn A, Krämer HH, Van Coster R, Schänzer A
Muscle Nerve. 2020 Feb; 61(2):173-181.
PMID: 31749205.

Abstract

Small fiber neuropathies (SFN) are associated with a reduction in quality of life. In adults, epidermal nerve fiber density (END) analysis is recommended for the diagnosis of SFN. In children, END assessment is not often performed. We analyzed small nerve fiber innervation to elucidate the potential diagnostic role of skin biopsies in young patients with pain.