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Papers of the Week


Papers: 16 Nov 2019 - 22 Nov 2019


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2020 Jan


Cephalalgia


40


1

Lasmiditan for the acute treatment of migraine: Subgroup analyses by prior response to triptans.

Authors

Knievel K, Buchanan AS, Lombard L, Baygani S, Raskin J, Krege JH, Loo L S, Komori M, Tobin J
Cephalalgia. 2020 Jan; 40(1):19-27.
PMID: 31744319.

Abstract

Lasmiditan demonstrated superiority to placebo in the acute treatment of migraine in adults with moderate/severe migraine disability in two similarly designed Phase 3 trials, SAMURAI and SPARTAN. Post-hoc integrated analyses evaluated the efficacy of lasmiditan in patients who reported a good or insufficient response to triptans and in those who were triptan naïve.