I am a
Home I AM A Search Login

Papers of the Week


Papers: 2 Nov 2019 - 8 Nov 2019


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2019 Oct 30


J Headache Pain


20


1

The appropriate dosing of erenumab for migraine prevention after multiple preventive treatment failures: a critical appraisal.

Authors

Ornello R, Tiseo C, Frattale I, Perrotta G, Marini C, Pistoia F, Sacco S
J Headache Pain. 2019 Oct 30; 20(1):99.
PMID: 31666008.

Abstract

Erenumab, a fully human monoclonal antibody directed against the calcitonin gene-related peptide receptor, was approved for the prevention of episodic (EM) or chronic migraine (CM) at the monthly dose of 70 mg or 140 mg. We reviewed the available literature to understand if patients with prior preventive treatment failures benefit more from the 140 mg dose than the 70 mg.