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Papers of the Week
Effect of genetic liability to migraine on coronary artery disease and atrial fibrillation: a Mendelian randomization study.
Abstract
Observational studies have implicated migraine as a risk factor for coronary artery disease (CAD) and atrial fibrillation (AF), however it is unclear whether migraine is causal in this relationship. We investigated potential causality between genetically instrumented liability to migraine and cardiovascular disease outcomes using two-sample Mendelian randomization.