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Papers of the Week


Papers: 19 Oct 2019 - 25 Oct 2019


Animal Studies, Pharmacology/Drug Development


2019 Oct 22


J Transl Med


17


1

Tibial post fracture pain is reduced in kinin receptors deficient mice and blunted by kinin receptor antagonists.

Authors

Minville V, Mouledous L, Jaafar A, Couture R, Brouchet A, Frances B, Tack I, Girolami J-P
J Transl Med. 2019 Oct 22; 17(1):346.
PMID: 31640792.

Abstract

Tibial fracture is associated with inflammatory reaction leading to severe pain syndrome. Bradykinin receptor activation is involved in inflammatory reactions, but has never been investigated in fracture pain.