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Papers of the Week


Papers: 5 Oct 2019 - 11 Oct 2019


Animal Studies


2020 Feb


Neurogastroenterol Motil


32


2

Endogenous control of inflammatory visceral pain by T cell-derived opioids in IL-10-deficient mice.

Authors

Basso L, Benamar M, Mas-Orea X, Deraison C, Blanpied C, Cenac N, Saoudi A, Dietrich G
Neurogastroenterol Motil. 2020 Feb; 32(2):e13743.
PMID: 31588671.

Abstract

The opioid-mediated analgesic activity of mucosal CD4 T lymphocytes in colitis has been reported in immunocompetent mice so far. Here, we investigated whether CD4 T lymphocytes alleviate from inflammation-induced abdominal pain in mice with defective immune regulation.