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Papers of the Week


Papers: 28 Sep 2019 - 4 Oct 2019


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Itch


2020 Jul


Br J Dermatol


183


1

Efficacy and safety of dupilumab in Japanese adults with moderate-to-severe atopic dermatitis: a subanalysis of three clinical trials.

Authors

Katoh N, Kataoka Y, Saeki H, Hide M, Kabashima K, Etoh T, Igarashi A, Imafuku S, Kawashima M, Ohtsuki M, Fujita H, Arima K, Takagi H, Chen Z, Shumel B, Ardeleanu M
Br J Dermatol. 2020 Jul; 183(1):39-51.
PMID: 31564057.

Abstract

Dupilumab, a human monoclonal antibody, blocks the shared receptor unit for interleukin-4 and interleukin-13. International phase II and III studies have evaluated the efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis (AD), but dupilumab effects in Japanese patients have not been reported.