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Papers of the Week


Papers: 10 Aug 2019 - 16 Aug 2019


Human Studies, Pharmacology/Drug Development


2019 Dec


J Arthroplasty


34


12

Preemptive Analgesia With Oxycodone Is Associated With More Pain Following Total Joint Arthroplasty.

Authors

Cooper JH, Lakra A, Maniker RB, Hickernell TR, Shah RP, Geller JA
J Arthroplasty. 2019 Dec; 34(12):2878-2883.
PMID: 31402074.

Abstract

Preemptive multimodal analgesia (PMA) is a commonly used technique to control pain following total joint arthroplasty. PMA protocols use multiple analgesics immediately preoperatively to prevent central sensitization and amplification of pain during surgery. While benefits of some individual components of a PMA protocol have been established, there are little data to support inclusion or exclusion of opioids in this context.