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Papers of the Week


Papers: 3 Aug 2019 - 9 Aug 2019


Human Studies


2020 Jan


Eur J Pain


24


1

Sympathetic efferent neurons are less sensitive than nociceptors to 4 Hz sinusoidal stimulation.

Authors

Jonas R, Namer B, Schnakenberg M, Soares S, Pakalniskis J, Carr R, Schmelz M, Rukwied R
Eur J Pain. 2020 Jan; 24(1):122-133.
PMID: 31392805.

Abstract

Sinusoidal current stimuli preferentially activate C-nociceptors. Sodium channel isoforms NaV1.7 and NaV1.8 have been implicated in this. Sympathetic efferent neurons lack NaV1.8 and were explored upon sinusoidal activation.