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Papers of the Week


Papers: 29 Jun 2019 - 5 Jul 2019


Human Studies, Pharmacology/Drug Development


2019 Oct


J Pain Symptom Manage


58


4

Additive Duloxetine for Cancer-related Neuropathic Pain Nonresponsive or Intolerant to Opioid-Pregabalin Therapy: A Randomized Controlled Trial (JORTC-PAL08).

Authors

Matsuoka H, Iwase S, Miyaji T, Kawaguchi T, Ariyoshi K, Oyamada S, Satomi E, Ishiki H, Hasuo H, Sakuma H, Tokoro A, Shinomiya T, Otani H, Otake Y, Tsukuura H, Matsumoto Y, Hasegawa Y, Kataoka Y, Otsuka M, Sakai K, et al.
J Pain Symptom Manage. 2019 Oct; 58(4):645-653.
PMID: 31254640.

Abstract

Although opioids and pregabalin are widely used for cancer-related neuropathic pain (CNP), no clinical trials exist to determine which medications are effective when an opioid-pregabalin combination therapy fails.