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Papers of the Week


Papers: 22 Jun 2019 - 28 Jun 2019

PAIN TYPE:
Migraine/Headache


2019 Jul


Cephalalgia


39


8

Differential efficacy of non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A meta-analysis.

Authors

de Coo IF, Marin J C, Silberstein SD, Friedman DI, Gaul C, McClure CK, Tyagi A, Liebler E, Tepper SJ, Ferrari MD, Goadsby PJ
Cephalalgia. 2019 Jul; 39(8):967-977.
PMID: 31246132.

Abstract

Two randomized, double-blind, sham-controlled trials (ACT1, ACT2) evaluated non-invasive vagus nerve stimulation (nVNS) as acute treatment for cluster headache. We analyzed pooled ACT1/ACT2 data to increase statistical power and gain insight into the differential efficacy of nVNS in episodic and chronic cluster headache.