I am a
Home I AM A Search Login

Papers of the Week


Papers: 18 May 2019 - 24 May 2019

PAIN TYPE:
Itch


2019 May 21


Immunity


50


5

Mast Cells Get on Your Nerves in Itch.

Authors

Voisin T, Chiu IM
Immunity. 2019 May 21; 50(5):1117-1119.
PMID: 31117004.

Abstract

Mast-cell-nerve interactions play an integral role in itch and inflammation. Meixiong et al. (2019) show that the receptors MRGPRB2 and FcεRI mediate distinct types of mast cell activation and nerve interactions and that mast cell activation through MRGPRB2 drives itch in allergic contact dermatitis.