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Papers of the Week


Papers: 18 May 2019 - 24 May 2019


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2019 Jul


Cephalalgia


39


8

Early onset of effect of onabotulinumtoxinA for chronic migraine treatment: Analysis of PREEMPT data.

Authors

Dodick DW, Silberstein SD, Lipton RB, Degryse RE, Adams A M, Diener H-C
Cephalalgia. 2019 Jul; 39(8):945-956.
PMID: 31112399.

Abstract

The Phase 3 REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) trials demonstrated efficacy/tolerability of onabotulinumtoxinA for headache prevention in adults with chronic migraine. This post hoc analysis assessed time of onset of onabotulinumtoxinA after the first treatment in total and responder populations and consistency weekly through five treatment cycles.