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Papers of the Week


Papers: 11 May 2019 - 17 May 2019


Human Studies

PAIN TYPE:
Migraine/Headache


2019 Oct


J Periodontol


90


10

Periodontal inflammation is related to increased serum calcitonin gene-related peptide (CGRP) levels in patients with chronic migraine.

Authors

Leira Y, Ameijeira P, Domínguez C, López-Arias E, Ávila P, Pérez-Mato M, Sobrino T, Campos F, D'Aiuto F, Leira R, Blanco J
J Periodontol. 2019 Oct; 90(10):1088-1095.
PMID: 31070784.

Abstract

Recently, a relationship was found between periodontitis and chronic migraine. Calcitonin gene-related peptide (CGRP) is a key element in migraine pathophysiology. However, no information exists of the potential association between periodontal inflammation and CGRP in chronic migraine. The aim of the study was, therefore, to investigate whether there is a link between periodontitis and peripheral levels of CGRP in a cohort of patients with chronic migraine.