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Papers of the Week


Papers: 4 May 2019 - 10 May 2019


Human Studies

PAIN TYPE:
Migraine/Headache


2019 Jul


Headache


59


7

Preliminary Evidence that Melatonin Is not a Biomarker With Children and Adolescents With Episodic Migraine.

Authors

Berger A, Litwin J, Allen I E, Qubty W, Irwin S, Waung M, Gelfand AA
Headache. 2019 Jul; 59(7):1014-1023.
PMID: 31054199.

Abstract

To date, there have not been reliable biomarkers to identify impending migraine episodes. A prior study in adults with migraine demonstrated a reduction in the urinary metabolic substrate of melatonin (urinary 6-sulfatoxymelatonin; aMT6s) during a migraine. The aim of this study was to examine whether evening urinary melatonin metabolite levels could predict migraine the next day in children and adolescents with migraine.