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Papers: 27 Apr 2019 - 3 May 2019
Animal Studies, Pharmacology/Drug Development
PAIN TYPE:
Migraine/Headache
2019 Apr 30
J Headache Pain
20
1
Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor are efficacious for the prevention of migraine headaches. The downstream molecular mechanisms following ligand-receptor blockade by which these antibodies prevent CGRP signaling through CGRP receptors have not been demonstrated.