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Papers of the Week


Papers: 20 Apr 2019 - 26 Apr 2019


Human Studies


2019 Apr 05


JAMA Netw Open


2


4

Association Between Opioid Dose Variability and Opioid Overdose Among Adults Prescribed Long-term Opioid Therapy.

Authors

Glanz JM, Binswanger IA, Shetterly SM, Narwaney KJ, Xu S
JAMA Netw Open. 2019 Apr 05; 2(4):e192613.
PMID: 31002325.

Abstract

Attempts to discontinue opioid therapy to reduce the risk of overdose and adhere to prescribing guidelines may lead patients to be exposed to variability in opioid dosing. Such dose variability may increase the risk of opioid overdose even if therapy discontinuation is associated with a reduction in risk.