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Papers of the Week


Papers: 6 Apr 2019 - 12 Apr 2019


Human Studies, Pharmacology/Drug Development


2019 May


Reg Anesth Pain Med


44


5

Prognostic value of hypersensitivity reactions on epidural steroid injection outcomes: a phenotypic signature? A prospective cohort study.

Authors

Cohen S, Doshi T, Dawson T, Gupta A, Durbhakula S, Constantinescu OC, Jacobs M, Verdun AV, Salisu M, Griffith SR, Kurihara C
Reg Anesth Pain Med. 2019 May; 44(5):586-594.
PMID: 30962251.

Abstract

Studies have found that diffuse pain, indicative of central sensitization, portends poor interventional outcomes. Multiple chemical sensitivities are associated with signs of central sensitization. We sought to prospectively determine whether hypersensitivity reactions (HR) were associated with epidural steroid injection (ESI) outcomes.