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Renthal W, Tochitsky I, Yang L, Cheng Y-C, Li E, Kawaguchi R, Geschwind DH, Woolf CJ
International Association for the Study of Pain
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Washington, D.C. 20005-1020
The IASP Pain Research Forum is a publication of the International Association for the Study of Pain
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Comments
Howard Fields, University of California San Francisco
Negus and colleagues have
Negus and colleagues have provided a useful in-depth review of the broad variety of approaches currently used to assay acute and chronic pain and the effect of analgesic drugs. The review is thorough, well referenced, nicely illustrated and provides a balanced and readable view of the strengths and weaknesses of each technique. In addition, the authors outline an innovative approach to characterize drugs using a matrix of different tests. I was particularly impressed with the sophisticated description of various conditioning approaches to assess both nociception and antinociceptive manipulations.