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Papers of the Week


Papers: 16 Mar 2019 - 22 Mar 2019


Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2019 Mar 14


Curr Pain Headache Rep


23


5

CGRP Antagonists for the Treatment of Chronic Migraines: a Comprehensive Review.

Authors

Urits I, Jones MR, Gress K, Charipova K, Fiocchi J, Kaye AD, Viswanath O
Curr Pain Headache Rep. 2019 Mar 14; 23(5):29.
PMID: 30874961.

Abstract

The purpose of the following review is to summarize the most recent understanding of migraine pathophysiology, as well as of basic and clinical science pharmacologic literature regarding the development of calcitonin gene receptor peptide (CGRP) antagonists as a novel therapeutic modality for the treatment of migraine headaches. A review is provided of erenumab, the first of its class FDA approved CGRP antagonist.