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Papers of the Week


Papers: 9 Feb 2019 - 15 Feb 2019


Animal Studies


2019 Feb 08


J Neuroinflammation


16


1

TNF-α/STAT3 pathway epigenetically upregulates Nav1.6 expression in DRG and contributes to neuropathic pain induced by L5-VRT.

Authors

Ding H-H, Zhang S-B, Lv Y-Y, Ma C, Liu M, Zhang K-B, Ruan X-C, Wei J-Y, Xin W-J, Wu S-L
J Neuroinflammation. 2019 Feb 08; 16(1):29.
PMID: 30736806.

Abstract

Studies showed that upregulation of Nav1.6 increased the neuronal excitability and participated in neuropathic pain in the dorsal root ganglion (DRG). However, the molecular mechanisms underlying Nav1.6 upregulation were not reported yet.