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Papers of the Week


Papers: 19 Jan 2019 - 25 Jan 2019


2019 Feb


J Psychosom Res


117

Central sensitization in chronic pain and medically unexplained symptom research: A systematic review of definitions, operationalizations and measurement instruments.

Authors

den Boer C, Dries L, Terluin B, van der Wouden JC, Blankenstein AH, van Wilgen PC, Lucassen P, van der Horst HE
J Psychosom Res. 2019 Feb; 117:32-40.
PMID: 30665594.

Abstract

Central sensitization (CS), a mechanism explaining the persistence of symptoms, has been the focus of many research projects. Explanations given to patients with chronic pain are often based on this mechanism. It is hypothesized that CS also plays an important role in the persistence of medically unexplained symptoms (MUS). However, definitions and operationalizations of CS vary. We conducted a systematic review of definitions, operationalizations and measurement instruments of CS.