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Papers of the Week


Papers: 5 Jan 2019 - 11 Jan 2019


Animal Studies


2019 Apr


Osteoarthritis Cartilage


27


4

Characterisation of peripheral and central components of the rat monoiodoacetate model of Osteoarthritis.

Authors

Lockwood SM, Lopes DM, McMahon SB, Dickenson AH
Osteoarthritis Cartilage. 2019 Apr; 27(4):712-722.
PMID: 30611904.

Abstract

Pain is the main reason patients report Osteoarthritis (OA), yet current analgesics remain relatively ineffective. This study investigated both peripheral and central mechanisms that lead to the development of OA associated chronic pain.