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Papers of the Week


Papers: 29 Dec 2018 - 4 Jan 2019


Animal Studies


2019 Jan 03


BMC Neurosci


20


1

Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats.

Authors

Roa-Coria J E, Pineda-Farias J B, Barragán-Iglesias P, Quiñonez-Bastidas G N, Zúñiga-Romero Á, Huerta-Cruz J C, Reyes-García J G, Flores-Murrieta F J, Granados-Soto V, Rocha-González H I
BMC Neurosci. 2019 Jan 03; 20(1):1.
PMID: 30602386.

Abstract

Peripheral diabetic neuropathy can be painful and its symptoms include hyperalgesia, allodynia and spontaneous pain. Hydrogen sulfide (HS) is involved in diabetes-induced hyperalgesia and allodynia. However, the molecular target through which HS induces hyperalgesia in diabetic animals is unclear. The aim of this study was to determine the possible involvement of transient receptor potential (TRP) channels in HS-induced hyperalgesia in diabetic rats.