research

The chronic pain crisis in North America persists and continues to be exacerbated by the opioid epidemic. As such, there is a great need for new and efficacious treatments…

Editor’s note: The North American Pain School (NAPS) took place 19-24 June 2022 in Montebello, Québec City, Canada.

Editor’s note: The North American Pain School (NAPS) took place 19-24 June 2022, in Montebello, Québec City, Canada.

How many potential analgesic drug targets identified in animal research have failed to reach clinical use? It’s an answer that’s hard to estimate, but the problem of mistranslation of…

In the classically aloof terminology of his time, 17th-century German physician Samuel Hafenreffer described pruritis, or itch, as an “unpleasant sensation that elicits the desire or reflex to scratch.”…

Each year since 1975, Nikon’s Small World has celebrated images captured by the light microscope. In their 2021 Photomicrography Competition, Nikon awarded fourth place to Paula Diaz, a PhD…

Pain education is an integral part of interventions to alleviate pain, with the goal of helping people with pain reconceptualize what pain actually is. Several campaigns such as Pain…

Editor’s note: The 2021 Australian Pain Society 41st Annual Scientific Meeting was held virtually April 19-20. This report summarizes a session at the meeting that argued for outside-of-the-box thinking…

While it is generally recognized that invertebrates experience the nociceptive aspects of pain, in the form of reflexive responses to noxious stimuli, there has been much debate about whether…

Which cells are responsible for painful cold sensing in teeth – the sensation that can accompany eating ice cream, drinking iced tea, or having an infected tooth? And which…

When it comes to chronic nerve injury pain, pro-inflammatory immune cells – microglia, in particular – receive the lion's share of attention. But new work shows that a specific…

Painful diabetic neuropathy remains a stubborn problem in many patients. While alterations in endogenous opioid signaling in the central nervous system (CNS) have been associated with this condition, both…

When it comes to venomous snakes, usually we think of these creatures as using venom to kill and eat their prey. However, a new study suggests that in one…