News

Nov 26 2020
High-Impact Chronic Pain: A Data Visualization
Fifty million of US adults have chronic pain, and 20 million of US adults have high-impact chronic pain (HICP). Age, sex, education level, employment status, and poverty status are major contributors to HICP.
news Research
Nov 23 2020
SARS-CoV-2 Interacts With Sensory Neurons
Clues are emerging to suggest where and how the virus attacks the peripheral nervous system.
news Research
Nov 12 2020
Chronic Pain or Current Pain: What Do Changes in Default Mode Network Functional Connectivity Actually Reflect?
Commonly seen changes in brain connectivity among fibromyalgia patients may more closely reflect these individuals’ current clinical pain state rather than their pain condition
news Research
Oct 20 2020
A Potassium Channel Mutation Drives Resilience to Labor Pain
A genetic variant in Kv6.4 leads to reduced labor pain in a subset of childbearing women
news Research

Papers of the Week

More

Community & Resource Updates

16th Neurostimulation Course: Advanced Pain Cadaver Course
4 Dec 2020 to 5 Dec 2020
Barcelona, Spain

See all Meetings & Events

Physician, NCCIH
Clinical Investigation Branch, National Center for Complementary and Integrative Health, National Institutes of Health
Bethesda, Maryland, US

See all Jobs

Community Updates Lower block

Forums

Nov 23 2020
The PRF Virtual Correspondents Blog – Cycle 2
PRF Correspondents

Twelve early-career pain researchers and clinicians are taking part in the second cycle of the...

1 Member Recommends
Discussion
Nov 16 2020
IASP PRF Seminar – Neuro-immune Crosstalk Contributes to Remission From Neuropathic Pain
PRF Team

Editor’s note: This seminar is the latest event in a series of seminars launched in May 2020 to help keep the pain research community...

Webinar

Start a new Discussion

Recent Comments

Aug 15 2020
By: John Quintner
About: A New Proposed Definition of Pain
Professor Harold Merskey, who was the chair of the original IASP...
News
Aug 12 2020
By: Eric Visser
About: A New Proposed Definition of Pain
Modified pain definition: An unpleasant sensory and emotional experience...
News
Jul 23 2020
By: John Quintner
About: A New Proposed Definition of Pain
Introducing the word "resembling" in relation to "the unpleasant sensory...
News
Jul 16 2020
By: PRF Executive Editor
About: A New Proposed Definition of Pain
The revised definition of pain has now been published in PAIN, along with...
News
May 15 2020
By: Johan Vlaeyen
About: Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
You may wish to have a look at some more recent updates of this paper: [1...
Paper
Mar 06 2020
By: Ashlie Reker
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
Editor's note: this comment is co-authored by Ashlie Reker and Steve...
Paper
Feb 24 2020
By: Steve Negus
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
An unexpected finding in this study was that CCI increased rather than...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Editor's note: This was the most popular paper on PRF over the past...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
Editor's Note: This paper was the most popular paper on PRF in 2019....
Paper
Sep 30 2019
By: Mamata Tamrakar
About: A New Proposed Definition of Pain
The pain threshold for each individual differs, which makes it more...
News
Sep 30 2019
By: John Quintner
About: A New Proposed Definition of Pain
In his introductory remarks, although Murat Aydede1 mentions the...
News
Sep 30 2019
By: Marc Mathys
About: A Causal Role for Long-Term Potentiation in Chronic Pain
Wonderful paper. Have the researchers found any evidence for differences...
News
Sep 14 2019
By: Murat Aydede
About: A New Proposed Definition of Pain
The news article states: "But one thing most agree on is that the...
News
Jul 13 2019
By: Howard Fields
About: Magnitude, response, and psychological determinants of placebo effects in chronic low-back pain: a randomised, double-blinded, controlled trial.
In this elegant study, the authors compare lidocaine injection of the...
Paper
Jun 03 2019
By: Howard Fields
About: Pain Management Best Practices Inter-Agency Task Force Report: Updates, Gaps, Inconsistencies, and Recommendations. Published May 9, 2019 by the US Department of Health.
Because of the epidemic of opioid overdose and the potential contribution...
Paper
Apr 01 2019
By: John Wood
About: Pain-in-a-Dish Expands the Nav1.7 Research Menu
In the accompanying paper, Bennett, Serra, and Tracey make an important...
News
Mar 29 2019
By: Howard Fields
About: Core Outcome Measures in Preclinical Assessment of Candidate Analgesics.
Negus and colleagues have provided a useful in-depth review of the broad...
Paper
Mar 14 2019
By: Markus Ploner
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
The study by Tan et al. represents a major step forward in understanding...
Paper
Jan 17 2019
By: Howard Fields
About: Hedonic drinking engages a supra-spinal inhibition of thermal nociception in adult rats.
This is an excellent paper investigating the analgesic effect of sucrose...
Paper
Nov 23 2018
By: Hiroshi Ueda
About: Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
This study seems to provide the first clinical evidence to support basic...
Paper
Oct 05 2018
By: Halina Machelska
About: Kappa Opioid Receptor Distribution and Function in Primary Afferents.
This is an interesting study confirming analgesic effects mediated by...
Paper
Aug 20 2018
By: Ru-Rong Ji
About: MicroRNA-30c-5p modulates neuropathic pain in rodents.
This is an interesting study with translational potential. The authors...
Paper
Aug 13 2018
By: Seena Ajit
About: miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus.
The conventional role of microRNAs (miRNAs) is to regulate gene expression...
Paper
Jun 18 2018
By: PRF Executive Editor
About: NIH Announces HEAL Initiative to Combat Opioid Crisis
Since publication of this news story, JAMA has published a Viewpoint by...
News
May 25 2018
By: Howard Fields
About: Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Drs. Yezierski and Hansson have provided a timely, readable, scholarly and...
Paper

Most Popular Content

Registered Users & Community

 

 

 

PRF registered users have full access to other registered users' profiles and can contact colleagues through the site. If you are not yet registered, it's free and easy to join the only web community dedicated to pain research.

 

Becoming a PRF registered user demonstrates your support for the Pain Research Forum and will contribute to the site's long-term success.

 

***REGISTER FOR THE IASP VIRTUAL SERIES ON PAIN & EXPO! MORE INFORMATION HERE***

 

                   ADVERTISEMENT

CLICK THE ADVERTISEMENT ABOVE TO REGISTER FOR THIS NOVEMBER 24th EVENT

Announcements

The PRF Correspondents are blogging!

***Take a look at the latest blog posts from the PRF Correspondents!***

 

Visit RELIEF News Today

RELIEF News is PRF's companion site for patients and the broader public. It provides plain language summaries of research news, feature articles, interviews and podcasts. Recent highlights include a podcast on complementary and integrative pain medicine, a news article on how opioids can sometimes increase pain, and interviews with leading experts in the field. Take a look--and sign up for the RELIEF monthly e-Newsletter and content alerts as well.