News

Feb 22 2021
I Feel Your Pain – and Analgesia
A new mouse study identifies an anterior cingulate cortex-to-nucleus accumbens brain circuit that regulates the social transfer of pain and pain relief.
news Research
Feb 16 2021
Understanding Pediatric Pain in Cultural and Medical Context
A recent IASP Virtual Series on Pain & Expo workshop focused on sociocultural influences on children’s pain.
news Conferences | Research
Feb 08 2021
Therapeutic Suggestions During General Anesthesia Reduce Postoperative Pain and Opioid Use
A recent clinical trial shows the benefits of positive suggestions for surgical patients
news Research
Jan 26 2021
Detecting Allergens and Triggering the Allergic Immune Response: A New Role for Sensory Neurons
TPRV1+ sensory neurons directly detect allergens in the skin and signal to dendritic cells via Substance P.
news Research

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Mar 03 2021
Psychologically Informed Physiotherapists With Good Communication Skills: A Conversation With Romy Parker
Y V Raghava Neelapala

Romy Parker, PhD, is a professor and director of the Pain Management Unit in the Department of Anaesthesia and Perioperative Medicine at the...

Interview
Feb 24 2021
IASP PRF Seminar – The Role of PRDM12 in Nociceptor Development From Embryogenesis to Adulthood
PRF Team

Editor’s note: This seminar is the latest event in a series of seminars launched in May 2020 to help keep the pain research community...

Webinar

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Recent Comments

Feb 03 2021
By: Andrew Wright
About: The Pain Beat (Episode 5) – The Coding of Sensory Information: Population Coding or Labeled Lines?
Thank you. I very much enjoyed the podcast; it was interesting and...
Interview
Aug 15 2020
By: John Quintner
About: A New Proposed Definition of Pain
Professor Harold Merskey, who was the chair of the original IASP...
News
Aug 12 2020
By: Eric Visser
About: A New Proposed Definition of Pain
Modified pain definition: An unpleasant sensory and emotional experience...
News
Jul 23 2020
By: John Quintner
About: A New Proposed Definition of Pain
Introducing the word "resembling" in relation to "the unpleasant sensory...
News
Jul 16 2020
By: PRF Executive Editor
About: A New Proposed Definition of Pain
The revised definition of pain has now been published in PAIN, along with...
News
May 15 2020
By: Johan Vlaeyen
About: Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art.
You may wish to have a look at some more recent updates of this paper: [1...
Paper
Mar 06 2020
By: Ashlie Reker
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
Editor's note: this comment is co-authored by Ashlie Reker and Steve...
Paper
Feb 24 2020
By: Steve Negus
About: The Operant Plantar Thermal Assay: A Novel Device for Assessing Thermal Pain Tolerance in Mice.
An unexpected finding in this study was that CCI increased rather than...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Editor's note: This was the most popular paper on PRF over the past...
Paper
Dec 18 2019
By: PRF Executive Editor
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
Editor's Note: This paper was the most popular paper on PRF in 2019....
Paper
Sep 30 2019
By: Mamata Tamrakar
About: A New Proposed Definition of Pain
The pain threshold for each individual differs, which makes it more...
News
Sep 30 2019
By: John Quintner
About: A New Proposed Definition of Pain
In his introductory remarks, although Murat Aydede1 mentions the...
News
Sep 30 2019
By: Marc Mathys
About: A Causal Role for Long-Term Potentiation in Chronic Pain
Wonderful paper. Have the researchers found any evidence for differences...
News
Sep 14 2019
By: Murat Aydede
About: A New Proposed Definition of Pain
The news article states: "But one thing most agree on is that the...
News
Jul 13 2019
By: Howard Fields
About: Magnitude, response, and psychological determinants of placebo effects in chronic low-back pain: a randomised, double-blinded, controlled trial.
In this elegant study, the authors compare lidocaine injection of the...
Paper
Jun 03 2019
By: Howard Fields
About: Pain Management Best Practices Inter-Agency Task Force Report: Updates, Gaps, Inconsistencies, and Recommendations. Published May 9, 2019 by the US Department of Health.
Because of the epidemic of opioid overdose and the potential contribution...
Paper
Apr 01 2019
By: John Wood
About: Pain-in-a-Dish Expands the Nav1.7 Research Menu
In the accompanying paper, Bennett, Serra, and Tracey make an important...
News
Mar 29 2019
By: Howard Fields
About: Core Outcome Measures in Preclinical Assessment of Candidate Analgesics.
Negus and colleagues have provided a useful in-depth review of the broad...
Paper
Mar 14 2019
By: Markus Ploner
About: Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception.
The study by Tan et al. represents a major step forward in understanding...
Paper
Jan 17 2019
By: Howard Fields
About: Hedonic drinking engages a supra-spinal inhibition of thermal nociception in adult rats.
This is an excellent paper investigating the analgesic effect of sucrose...
Paper
Nov 23 2018
By: Hiroshi Ueda
About: Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study.
This study seems to provide the first clinical evidence to support basic...
Paper
Oct 05 2018
By: Halina Machelska
About: Kappa Opioid Receptor Distribution and Function in Primary Afferents.
This is an interesting study confirming analgesic effects mediated by...
Paper
Aug 20 2018
By: Ru-Rong Ji
About: MicroRNA-30c-5p modulates neuropathic pain in rodents.
This is an interesting study with translational potential. The authors...
Paper
Aug 13 2018
By: Seena Ajit
About: miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus.
The conventional role of microRNAs (miRNAs) is to regulate gene expression...
Paper
Jun 18 2018
By: PRF Executive Editor
About: NIH Announces HEAL Initiative to Combat Opioid Crisis
Since publication of this news story, JAMA has published a Viewpoint by...
News

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