Aug 10 2018
A recent study suggests the presence of sampling bias in human pain studies, but the effects are modest
news Research
Jul 16 2018
Nanobody biosensor reveals that peptides activate opioid receptors first at the plasma membrane and then in endosomes, while drugs also propel activation in the Golgi apparatus
news Drug Development | Research
Jul 02 2018
A recent mouse study identifies cells that regulate alloknesis through Piezo2
news Research
Jun 19 2018
Disrupting the interaction among opioid receptors, vasopressin receptors, and beta-arrestin-2 offers a potential strategy to slow tolerance in humans, though questions remain
news Drug Development | Research

Papers of the Week

Community & Resource Updates

22 Aug 2018 to 25 Aug 2018
San Diego, California, US
Registration Deadline:
22 Aug 2018
University of Colorado
Boulder, Colorado, US

Community Updates Lower block


Aug 15 2018

Editor’s note: The third North American Pain School (NAPS) took place June 24-28, 2018, in...

Aug 06 2018

Editor’s note: The third North American Pain School (NAPS) took place June 24-28, 2018, in Montebello, Quebec,...


Recent Comments

Aug 20 2018
This is an interesting study with translational potential. The authors...
Aug 13 2018
The conventional role of microRNAs (miRNAs) is to regulate gene expression...
Jun 18 2018
Since publication of this news story, JAMA has published a Viewpoint by...
May 25 2018
Drs. Yezierski and Hansson have provided a timely, readable, scholarly and...
May 24 2018
How an organism maintains its internal stability despite variations in...
May 15 2018
By: Mark Hoon
Four years ago, the labs of Patrik Ernfors and Sten Linnarsson from the...
Apr 17 2018
Pain in surgical joint instability models of osteoarthritis (OA) is...
Mar 30 2018
This is an interesting study that has demonstrated palmitoylation as a...
Mar 23 2018
This is a very interesting study from the labs of Andrew Todd and Mark...
Feb 12 2018
Dr. Clauw and his colleagues clearly favoured "centralized" as the third...
Feb 06 2018
The medial frontal cortex (MFC) contains multiple regions under intense...
Jan 17 2018
Editor's note: This comment is co-authored by Rafael González-Cano and...
Dec 18 2017
The Cell paper focused on the acute effects of the novel opioid agonists,...
Nov 26 2017
This is a very thorough study that examines a group of structurally...
Nov 05 2017
Surprising that the tendency for co-morbidity of different conditions did...
Nov 02 2017
I agree, low pH associated with infection, injury or ischemia will favor...
Q & A
Oct 06 2017
By: Ted Price
This comment is coauthored by Ted Price, Head of Neuroscience, UT Dallas;...
Jul 27 2017
Dr. Hesselink: Very interesting, thank you for sharing. I have often...
Jun 20 2017
This paper is quite important, also from a clinical point of view. It is...
Jun 18 2017
At the NeuPSIG at Gothenburg on the 17th of June, a poster was presented...
May 02 2017
This comment is co-authored by Andrey Ryabinin and Mary Heinricher, Oregon...
May 02 2017
I admit that I read the paper by Ryabinin and colleagues with interest,...
Apr 13 2017
This comment is co-authored by Andrey Ryabinin and Mary Heinricher, Oregon...
Apr 05 2017
By: Ke Ren
The authors report interesting findings that electro-acupuncture (EA) in...

Members & Community

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Research Resources

Information for the new researcher or veteran in the field, Pain 101 is our growing collection of topical articles on important issues in pain research. Check out our articles on modeling pain in lower organisms, the role of glia in chronic pain, and transcranial magnetic stimulation. Our Pain Genes Resource will have the most up-to-date information on the genetics of pain sensitivity, risk of chronic pain and response to analgesics, presented in a format that makes it easy to keep current. We're in the process of pulling together data on the first  53 genes—you can help this resource grow by submitting new genes and studies. Stay tuned for more resources to come, including our Drug Pipeline database.