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Bringing the Epidemiological Perspective to Pain Research: A Conversation with Gary Macfarlane

by Pauline Voon on 1 Aug 2016

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Editor’s Note: The first-ever North American Pain School (NAPS) took place June 26-30, 2016, in Montebello, Quebec, Canada.

Interview

Webinar: Dorsal Horn Circuits Underlying Touch-Evoked Pain After Nerve Injury

by PRF Team on 15 Jun 2016

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On June 15, Reza Sharif-Naeini gave a talk on his recent research on dorsal horn pain circuitry (see PRF related news story). After his talk, there was a panel…

Webinar

Webinar: The Role of Autoantibodies in Rheumatoid Arthritis Joint Pain

by PRF Team on 26 Apr 2016

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On April 19, Camilla Svensson gave a talk on the potential pathogenic role of autoantibodies in the induction of pain in rheumatoid arthritis. After her talk, there was a…

Webinar

Modality-Specific TRPV1 Antagonist Analgesia: What Are the Prospects?

by Michel Pare on 9 Feb 2015

Editors’ note: PRF member Michel Paré is president and co-founder of PhylogenX, a contract research organization in Montreal, Canada. Paré submitted the following comment about a new TRPV1 blocker…

Discussion

Last comment: PRF Team, 1 Feb 2016

UPDATE: NEOMED has received approval from Health Canada to begin a phase II clinical trial of NEO6860, its TRPV1 antagonist, for the treatment of osteoarthritis pain. Read more at http://neomed.ca/en/neomed-to-initiate-its-first-phase-ii-clinical-trial-in-canada/
…

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Q & A: A Question About Place Preference Boxes

by Steve Davidson on 16 Oct 2015

Editor’s Note: We are pleased to announce Q & A, a new Forums feature that will give PRF members and readers the opportunity to ask the community for answers…

Q & A

Webinar: Safer Opioid Analgesics: It’s All in the Telling of the Tail

by PRF Team on 21 Jan 2016

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On January 21, Gavril Pasternak gave a talk on the promise of mu opioid receptor splice variants as a path to safer opioid therapies for pain. After his talk,…

Webinar

Webinar: Targeting Unusual Voltage-Gated Sodium Currents for Pain Therapy

by PRF Team on 26 Oct 2015

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On October 23, Ted Cummins, Indiana University, US, gave a talk on the promise of voltage-gated sodium channels as analgesic targets. After his talk, there was a panel discussion... …

Webinar

Access to Raw Behavioral Data From Preclinical Research Papers

by Rosemary Morland on 21 Sep 2015

Editor’s note: Rosemary Morland completed postdoctoral work with Andrew Rice at Imperial College London, UK, and is now a freelance medical writer and editor. Morland submitted the following comment…

Discussion

Last comment: Peter Kamerman, 28 Sep 2015

Thanks for a great article Rosemary.

This is an important topic, and one in which medical sciences lag far behind other fields. I had not directly encountered the issue until… more

Webinar: Chronic Low Back Pain: Preclinical and Clinical Perspectives

by PRF Team on 25 Sep 2015

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On September 25, Laura Stone gave a talk on some of the latest research that is advancing the understanding of chronic low back pain. After her talk, there was…

Webinar

Closing the Sex Gap in Preclinical Pain Research

by Stephani Sutherland on 27 May 2015

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Investigators agree that both males and females should be included in preclinical studies, but should the National Institutes of Health require it?

Discussion

Webinar: Sickle Cell Pain

by PRF Team on 16 Jun 2015

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On June 16, Cheryl Stucky, Medical College of Wisconsin, Milwaukee, US, gave a talk describing the problem of sickle cell pain, mechanisms underlying the disease, and the latest research…

Webinar

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Elucidating the Pathophysiology of Peripheral Neuropathies: A Conversation With Claudia Sommer

by Neil Andrews on 10 Mar 2015

This is the eighth in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

Webinar: Pain Epigenetics: Current Research and Future Challenges

by PRF Team on 16 Apr 2015

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On April 16, Stephen McMahon and Franziska Denk, King’s College London, UK, gave a talk on the latest findings on pain epigenetics. After their talk, there was a panel…

Webinar

In Memoriam: Jean-Marie Besson (1938-2014)

by Tony Dickenson on 9 Mar 2015

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Editor's Note: This remembrance of pioneering pain researcher Jean-Marie Besson was co-authored by Tony Dickenson, University College London, UK, and Luis Villaneuva, Centre de Psychiatrie et Neurosciences, INSERM UMR…

Discussion

Webinar: Personalized Pain Medicine: Improving Diagnosis and Treatment of Complex Persistent Pain Conditions

by PRF Team on 18 Mar 2015

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On March 18, William Maixner, University of North Carolina at Chapel Hill, US, gave a talk on what the present and future look like for personalized pain medicine. After…

Webinar

Patients as Whole Human Beings: A Conversation With Eija Kalso

by Neil Andrews on 11 Feb 2015

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This is the seventh in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

A Non-Pharmacological Approach to Pain: A Conversation With M. Catherine Bushnell

by Neil Andrews on 29 Jan 2015

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This is the sixth in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

Webinar: Targeting Calcitonin Gene-Related Peptide (CGRP) for Prevention of Migraine

by PRF Team on 12 Feb 2015

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On February 12, Marcelo Bigal, Teva Pharmaceutical Industries, Frazer, Pennsylvania, US, gave a talk on CGRP as a target for prevention of migraine, with a focus on anti-CGRP antibodies…

Webinar

The Value of Animal Models of Pain: A Conversation With Frank Porreca

by Neil Andrews on 5 Jan 2015

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This is the fifth in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

Paper: Representation of Aversive Prediction Errors in the Human Periaqueductal Gray

by Timothy Meeker on 17 Nov 2014

Editors' Note: Tim Meeker, a PhD student working with Joel Greenspan and David Seminowicz at the University of Maryland, Baltimore, US, recently led a Journal Club discussing work from…

Journal Club

Last comment: Mathieu Roy, 22 Dec 2014

This comment was coauthored by Tor Wager.

We thank the Pain Research Forum and Tim Meeker for discussing our paper. We share many of his questions and ideas about future… more

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In Memoriam: Edward Perl (1926-2014)

by Alan Light on 5 Aug 2014

Editors' Note: Alan Light, University of Utah, Salt Lake City, US, remembers the life and work of a pioneering pain researcher. We invite you to share your memories of…

Discussion

Last comment: Mark Zylka, 19 Dec 2014

Perl Memorial Lecture to honor the life and work of Dr. Edward Perl, January 23, 2015.

As nicely described by Dr. Light above, Dr. Edward Perl spent the majority of… more

Webinar: Circulating MicroRNAs as Biomarkers, Therapeutic Targets, and Signaling Molecules

by PRF Team on 14 Jan 2015

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On January 14, Seena Ajit, Drexel University College of Medicine, Philadelphia, US, gave a talk on the emerging role of microRNAs in pain. After her talk, there was a…

Webinar

From the Lab to the Clinic and Back Again: A Conversation With David Bennett

by Neil Andrews on 10 Dec 2014

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This is the fourth in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

Moving From Pain to Addiction Research: A Conversation With Howard Fields

by Neil Andrews on 18 Nov 2014

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This is the third in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

Webinar: Design and Conduct of Clinical Trials of Analgesics

by PRF Team on 24 Nov 2014

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On November 24, Nathaniel Katz, Analgesic Solutions, Natick, US, gave a talk on factors important for clinical trial testing of new pain medications. After his talk, there was a…

Webinar

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Diverse Interests in the Basic Science of Pain: A Conversation With Ru-Rong Ji

by Neil Andrews on 28 Oct 2014

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This is the second in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

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Webinar: The Use of Animal Models of Pain in Drug Discovery: Considerations and Challenges

by PRF Team on 29 Oct 2014

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On October 29, Jim Pomonis, American Preclinical Services, Minneapolis, US, gave a talk on the use of animal models of pain in drug discovery. After his talk, there was…

Webinar

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Capitalizing on Neuronal Plasticity to Develop New Analgesic Drugs: A Conversation With Ted Price

by Neil Andrews on 3 Oct 2014

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This is the first in a series of Forum interviews with PRF’s eight new science advisors for 2014-2015.

Interview

Webinar: Building a Better Aspirin: The Frontiers of Pain Medicine Development

by PRF Team on 10 Sep 2014

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The PRF webinar with speaker William Schmidt is now available for viewing. Access the presentation and panel discussion below. Schmidt, of NorthStar Consulting, Davis, California, US, gave a talk on…

Webinar

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Webinar: Autoimmune Causes of Chronic Pain

by PRF Team on 26 Jun 2014

The June 26 webinar with speaker Andreas Goebel is now available for viewing. Access the presentation and panel discussion below. Goebel, of the University of Liverpool and The Walton Centre…

Webinar

Last comment: Cort Johnson, 4 Aug 2014

Thanks for the webinar. I run a Chronic Fatigue Syndrome and Fibromyalgia information website and we recently posted a blog r eviewing the webinar.

I was struck by the… more

A Nation in Pain: Healing our Biggest Health Problem (Book Review)

by Howard Fields on 1 May 2014

Judy Foreman has written a remarkable book about pain. Although aimed at an educated and curious non-professional readership it contains information and perspective that will be of great value…

Discussion

Last comment: Neil Andrews, 15 May 2014

I think it is worth a mention here that Judy Foreman recently received the 2014 Kathleen Foley Journalist Award from the American Pain Society. The honor, presented at the… more

Webinar: Paradigm Shifts in Migraine Science: New Opportunities for Therapy and Implications for Other Pain Disorders

by PRF Team on 17 Apr 2014

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The April 17 webinar with speaker Andrew Charles is now available for viewing. Access the presentation and panel discussion below.

Webinar

Sensitization and Catastrophizing: Introspection Confirmed Experimentally

by Carl L von Baeyer on 25 Feb 2014

I had a strange experience recently. My own reaction to it seemed interesting enough to warrant closer examination, and that, in turn, led to a useful insight. Eighteenth century…

Discussion

Last comment: Simon van Rysewyk, 25 Feb 2014

Hi Carl,

This article wonderfully demonstrates the effectiveness of investigator-subjects and introspection in pain research. Donald D. Price advocates this approach. I wonder if this method has been used in… more

Webinar: Translating Science into Treatment: The Example of Visceral Pain

by PRF Team on 11 Mar 2014

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Editors' Note: The March 11 webinar with speaker Qasim Aziz is now available for viewing. Access the presentation and panel discussion below.

Webinar

Webinar: Targeting Translation Control Mechanisms to Ease Pain

by PRF News Editor on 19 Dec 2013

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Editors' note: The January 14 webinar with speaker Ted Price is now available for viewing. Access the presentation and panel discussion below.

Webinar

Paper: Naturalistic Parental Pain Management During Immunizations During the First Year of Life: Observational Norms From the OUCH Cohort

by Ayala Gorodzinsky, Line Caes on 18 Dec 2013

The Centre for Pediatric Pain Research at IWK Health Centre, Halifax, Canada, recently met to discuss the study by Diana Lisi of York University, Toronto, Canada, and colleagues examining…

Journal Club

Last comment: Rebecca Pillai Riddell, 19 Dec 2013

RPR: Thanks for contacting me to offer some thoughts on the ethical perspectives of our OUCH cohort study. Our observational study (which followed 760 families on up to four… more

Webinar: Picturing Pain in the Brain

by PRF News Editor on 19 Nov 2013

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Editors' note: The December 16 webinar with speaker Tor Wager is now available for viewing. Access the presentation and panel discussion below.

Webinar

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Webinar: Exploring Neuron-Glia Crosstalk in Pain

by PRF News Editor on 1 Oct 2013

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Editors' note: The October 30 webinar with speaker Michael Salter is now available for viewing. Access the presentation and panel discussion below.

Webinar

Webinar: A Cellular Perspective on Pain

by PRF News Editor on 6 Aug 2013

Editors' note: The September 12th webinar with speaker Jon Levine is now available for viewing. Access the presentation and panel discussion below.

Webinar

Last comment: Mayank Gautam, 12 Sep 2013

Thanks for such a great webinar. I feel very glad after joining this forum. Each word during the presentation and discussion seems to be a new path to follow… more

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The Intersection of Fungal Inoculation, Diagnosis, and Pain Management: Commentary on the Consumer Experience With Unsafe Products and Practices

by Terri Lewis on 8 Jul 2013

Editors' Note: PRF member Terri Lewis is a rehabilitation counselor and volunteer patient advocate. Lewis submitted the following perspective and commentary on the fungal meningitis outbreak that occurred when…

Discussion

Last comment: Richard Dobson, 9 Aug 2013

While perusing the PRF site, I found some interesting information in an interview with Dr. Anne Louise Oaklander. Many people with chronic back pain are poorly understood and misdiagnosed,… more

Opioids and Road Trauma: Is It the Medicine, the Pain, or Both?

by PRF News Editor on 12 Feb 2013

At a time of increasing concern among physicians, public health advocates, and the lay public about the adverse consequences of high-dose opioids for chronic non-cancer pain, new research on…

Discussion

Last comment: Richard Dobson, 9 Jul 2013

The physical and neurologic impact of chronic pain simply has not been explored, in my opinion. For example, pain is a major risk factor for falls and medications are… more

Lost in Translation: Improving the Validity of Animal Models Used in the Study of Neuropathic Pain

by PRF News Editor on 27 Jun 2013

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Editors' note: The June 27th webinar with speaker Andrew S.C. Rice is now available for viewing. Access the presentation and panel discussion below.

Webinar

Webinar and Live Discussion: Measuring the Affective Dimensions of Pain in Animal Models

by PRF News Editor on 20 May 2013

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Editors' note: The presentation by Frank Porreca on Preclinical Assessment of Affective Dimensions of Pain to Enhance Translation is now available for viewing. Access the presentation and panel discussion…

Webinar

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US National Institutes of Health Releases First Federal Plan to Advance Research on Overlapping Pain Conditions

by Christin Veasley on 12 Mar 2013

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Editors’ note: Christin Veasley, the Executive Director of the National Vulvodynia Association and Co-founder of the Chronic Pain Research Alliance sent this report on an August 2012 NIH workshop…

Discussion

A Long Way to Go: A Grad Student’s View of the Neurobiology of Disease Workshop at Neuroscience 2012, New Orleans

by Shan Lou on 7 Feb 2013

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How much do we know about pain? Which would you choose from 0-10? In the Neurobiology of Disease workshop, held in conjunction with the Society for Neuroscience meeting in…

Discussion

Paper: What Is Spontaneous Pain and Who Has It?

by Steve Davidson, Daniel Brenner on 3 Jan 2013

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Editors' Note: Thanks to Steve Davidson and Daniel Brenner of Washington University Medical School, St. Louis, US, for submitting this Journal Club. The Wash U Pain & Itch Journal Club…

Journal Club

Paper: Predicting Adult Outcomes from Childhood Pain Profiles

by Kathryn Birnie, Line Caes on 9 Nov 2012

Editors' Note: Rich, insightful conversations about current research go on every day in journal clubs around the world. The goal of our new Journal Club feature is to capture…

Journal Club

Last comment: Lynn Walker, 13 Nov 2012

Editors’ Note: Questions from Kathryn Birnie and Line Caes, the authors of the Journal Club, appear in italics below.

It is a great treat to read these reflections regarding our… more

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Discovery and Translation: Do We Have the Right Strategy?

by Robert Yezierski on 22 Oct 2012

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There is little doubt that there have been far too many quiet moments when it comes to talking about the success of translational pain research. Over the past five…

Discussion

Paper: Maladaptive dendritic spine remodeling contributes to diabetic neuropathic pain

by Carter Jones on 10 Oct 2012

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This article identified morphologic changes occurring in dendritic spines, the sites of postsynaptic communication on neurons of the spinal cord dorsal horn that coincide with the development of behavioral…

Journal Club

The Power of the Collective: A Conversation with Stephen McMahon

by PRF News Editor on 29 Jun 2012

Stephen McMahon, PhD, casts a wide net to catch the molecular mediators of pain. His lab at King’s College London in the UK uses techniques from molecular biology and…

Interview

Progress through collaboration

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The IASP Pain Research Forum is a publication of the International Association for the Study of Pain