|
|
HTR2A |
5-hydroxytryptamine (serotonin) receptor 2A |
13 |
47,407,513: 47,470,369 |
receptor for the neurotransmitter serotonin |
musculoskeletal pain, irritable bowel syndrome, analgesia requirements, other |
13 |
| Summary: |
|
|
|
ATL1 |
atlastin GTPase 1 |
14 |
50,069,550: 50,169,534 |
endoplasmic reticulum GTP-binding protein |
Hereditary Sensory and Autonomic Neuropathy Type ID |
1 |
| Summary: |
|
|
|
CCT5 |
chaperonin-containing TCP1, subunit 5 (epsilon) |
5 |
10,250,282: 10,266,500 |
molecular chaperone |
sensory neuropathy |
1 |
| Summary: |
Text to come. |
|
|
DNMT1 |
DNA (cytosine-5-)-methyltransferase-1 |
19 |
10,244,023:10,305,755 |
controls gene expression through DNA methylation |
hereditary sensory and autonomic neuropathy type I with dementia and hearing loss (HSAN IE) |
1 |
| Summary: |
Text to come. |
|
|
ESR1 |
estrogen receptor 1 |
6 |
152,128,454: 152,424,406 |
nuclear estrogen receptor |
migraine, dysmenorrhea, osteoarthritis pain |
13 |
| Summary: |
|
|
|
FAM134B |
family with sequence similarity 134, member B |
5 |
16,473,148: 16,617,118 |
Required for long-term survival of nociceptive and autonomic ganglion neurons |
Hereditary Sensory and Autonomic Neuropathy Type IIB (HSAN2B) |
3 |
| Summary: |
|
|
|
FAAH |
fatty acid amide hydrolase |
1 |
46,859,939: 46,879,520 |
inactivates the endocannabinoid anandamide |
experimental cold pain, functional GI disorders, Parkinson disease |
3 |
| Summary: |
Text to come. |
|
|
GCH1 |
GTP cyclohydrolase 1 |
14 |
55,308,724: 55,369,542 |
rate-limiting enzyme for BH4 synthesis |
acute and chronic pain, experimental pain |
13 |
| Summary: |
|
|
|
IKBKAP |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
9 |
111,629,801: 111,696,608 |
scaffold protein and regulator of proinflammatory signaling |
Hereditary Sensory and Autonomic Neuropathy Type III (HSAN3) or Familial Dysautonomia |
3 |
| Summary: |
|
|
|
IL1A |
interleukin 1, alpha |
2 |
113,531,493: 113,542,971 |
cytokine produced by activated machrophages and involved in the inflammatory response |
low back pain |
2 |
| Summary: |
|
