The risk for developing TMD was increased in people homozygous for low (H1) or high (H2, H3) expressing haplotypes, but decreased in high/low heterozygotes.
Park et al. also tested rs1042713 and found no association.
Xiao et al. report decreased heterozygosity in fibromyalgia group, and a trend toward lower risk with A allele. Hocking et al. was negative for association with 7 other SNPs in ADRB2 and 11 SNPs in COMT.
Study was negative for association with 7 other SNPs in ADRB2 and 11 SNPs in COMT.
Study was negative for 4 other SNPs in ADRB2 and 8 in COMT.
Haplotype was associated with increased risk of FM in Spanish and Mexican women.
Negative result: No association with migraine in women.
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