Papers: 23 Jun 2012 - 29 Jun 2012

Editors' Pick

Methylglyoxal activates nociceptors through TRPA1 - a possible mechanism of metabolic neuropathies.

Eberhardt MJ, Filipovic MR, Leffler A, de la Roche J, Kistner K, Fischer MJ, Fleming T, Zimmermann K, Ivanovic-Burmazovic I, Nawroth PP, Bierhaus A, Reeh PW, Sauer SK

J Biol Chem. 2012 Jun 27.

PMID: 22740698.

Abstract

Editors' Pick

Divorce of obligatory partners in pain: disruption of GABA(B) receptor heterodimers in neuralgia.

Benke D, Zeilhofer H U

EMBO J. 2012 Jun 26.

PMID: 22735189.

Abstract

Editors' Pick

Link Between Pain and Olfaction in an Inherited Sodium ChannelopathyInherited Sodium Channelopathy.

Zufall F, Pyrski M, Weiss J, Leinders-Zufall T

Arch Neurol. 2012 Jun 25:1-5.

PMID: 22733046.

Abstract

Editors' Pick

Tailored treatment of peripheral neuropathic pain.

Sindrup SH, Finnerup NB, Jensen TS

Pain. 2012 Jun 22.

PMID: 22727536.

Abstract

Editors' Pick

An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of th

Huggins JP, Smart TS, Langman S, Taylor L, Young T

Pain. 2012 Jun 20.

PMID: 22727500.

Abstract

Editors' Pick

A nociceptive signaling role for neuromedin B.

Mishra SK, Holzman S, Hoon MA

J Neurosci. 2012 Jun 20; 32(25):8686-95.

PMID: 22723708.

Abstract

Editors' Pick

Integrative Approach to Pain Genetics Identifies Pain Sensitivity Loci across Diseases.

Ruau D, Dudley JT, Chen R, Phillips NG, Swan GE, Lazzeroni LC, Clark DJ, Butte AJ, Angst MS

PLoS Comput Biol. 2012 Jun; 8(6):e1002538. Epub 2012 Jun 07.

PMID: 22685391.

Abstract

Neurochemical features of boar lumbo-sacral dorsal root ganglion neurons and characterization of sensory neurons innervating the urinary bladder trigone.

Russo D, Clavenzani P, Sorteni C, Bo Minelli L, Botti M, Gazza F, Panu R, Ragionieri L, Chiocchetti R

J Comp Neurol. 2012 Jun 27.

PMID: 22740069.

Abstract

Differential Effects of Peripheral versus Central Coadministration of QX-314 and Capsaicin on Neuropathic Pain in Rats.

Shen J, Fox LE, Cheng J

Anesthesiology. 2012 Jun 26.

PMID: 22739765.

Abstract

Nestin immune labeling in human adult trigeminal ganglia.

Rusu M C, Hostiuc S, Loreto C, Păduraru D

Acta Histochem. 2012 Jun 25.

PMID: 22739577.

Abstract

Etodolac Blocks the Allyl Isothiocyanate-Induced Response in Mouse Sensory Neurons by Selective TRPA1 Activation.

Inoue N, Ito S, Nogawa M, Tajima K, Kyoi T

Pharmacology. 2012 Jun 27; 90(1-2):47-54.

PMID: 22739568.

Abstract

Mechanical and Heat Hyperalgesia Highly Predict Clinical Pain Intensity in Patients With Chronic Musculoskeletal Pain Syndromes.

Staud R, Weyl EE, Price DD, Robinson ME

J Pain. 2012 Jun 26.

PMID: 22739051.

Abstract

Nav(1.8)igating the maze of sensory function.

Tate S, Derjean D, Rugiero F

Pain. 2012 Jun 25.

PMID: 22738797.

Abstract

The efficacy of acupuncture in human pain models: A randomized, controlled, double-blinded study.

Rebhorn C, Breimhorst M, Buniatyan D, Vogel C, Birklein F, Eberle T

Pain. 2012 Jun 25.

PMID: 22738796.

Abstract

7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as Selective CB2 Cannabinoid Receptor Ligands: Structural Investigations around a Novel Class of Full Agonists.

Baraldi P G, Saponaro G, Moorman AR, Romagnoli R, Preti D, Baraldi S, Ruggiero E, Varani K, Targa M, Vincenzi F, Borea P A, Aghazadeh Tabrizi M

J Med Chem. 2012 Jun 28.

PMID: 22738271.

Abstract

Glia as a Link between Neuroinflammation and Neuropathic Pain.

Jha M K, Jeon S, Suk K

Immune Netw. 2012 Apr; 12(2):41-7.

PMID: 22740789.

Abstract

Orally Active Adenosine A(1) Receptor Agonists with Antinociceptive Effects in Mice.

Korboukh I, Hull-Ryde EA, Rittiner JE, Randhawa AS, Coleman J, Fitzpatrick BJ, Setola V, Janzen WP, Frye SV, Zylka MJ, Jin J

J Med Chem. 2012 Jun 27.

PMID: 22738238.

Abstract

Microglia and intractable chronic pain.

Tsuda M, Beggs S, Salter MW, Inoue K

Glia. 2012 Jun 27.

PMID: 22740331.

Abstract

Let-7 microRNAs and Opioid Tolerance.

He Y, Wang Z J

Front Genet. 2012; 3:110.

PMID: 22737161.

Abstract

Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury.

Kobayashi K, Yamanaka H, Yanamoto F, Okubo M, Noguchi K

Glia. 2012 Jun 26.

PMID: 22736439.

Abstract

The negative feedback regulation of TRPV4 Ca(2+) ion channel function by its C-terminal cytoplasmic domain.

Chun J, Shin S H, Kang S S

Cell Signal. 2012 Jun 23.

PMID: 22735813.

Abstract

A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors.

Hunt RF, Hortopan GA, Gillespie A, Baraban SC

Exp Neurol. 2012 Jun 24.

PMID: 22735490.

Abstract

Suppression of neurokinin-1 receptor in trigeminal ganglia attenuates central sensitization following inflammation.

Takeda M, Takahashi M, Matsumoto S

J Peripher Nerv Syst. 2012 Jun; 17(2):169-81.

PMID: 22734902.

Abstract

Endocannabinoid modulation of jejunal afferent responses to LPS.

Donovan J, Grundy D

Neurogastroenterol Motil. 2012 Jun 27.

PMID: 22734449.

Abstract

TRPV1: a stress response protein in the central nervous system.

Ho KW, Ward NJ, Calkins DJ

Am J Neurodegener Dis. 2012 May 30; 1(1):1-14.

PMID: 22737633.

Abstract

Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes.

Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang S H, Morisseau C, Haj FG, Hammock BD

Proc Natl Acad Sci U S A. 2012 Jun 25.

PMID: 22733772.

Abstract

Transient opening of the perineurial barrier for analgesic drug delivery.

Hackel D, Krug SM, Sauer R-S, Mousa SA, Böcker A, Pflücke D, Wrede E-J, Kistner K, Hoffmann T, Niedermirtl B, Sommer C, Bloch L, Huber O, Blasig IE, Amasheh S, Reeh PW, Fromm M, Brack A, Rittner HL

Proc Natl Acad Sci U S A. 2012 Jun 25.

PMID: 22733753.

Abstract

Neural processing of sensory and emotional-communicative information associated with the perception of vicarious pain.

Vachon-Presseau E, Roy M, Martel MO, Albouy G, Chen J, Budell L, Sullivan MJ, Jackson PL, Rainville P

Neuroimage. 2012 Jun 23.

PMID: 22732556.

Abstract

Causes and prevention of chronic postsurgical pain.

Van de Ven TJ, John Hsia H-L

Curr Opin Crit Care. 2012 Jun 22.

PMID: 22732437.

Abstract

The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-Kinase signaling and formalin-specific receptors.

Coste O, Möser CV, Sisignano M, Kynast KL, Minden A, Geisslinger G, Niederberger E

Behav Brain Res. 2012 Jun 23.

PMID: 22732262.

Abstract

Analysis of sphingolipid and prostaglandin synthesis during zymosan-induced inflammation.

Linke B, Schreiber Y, Zhang D D, Pierre S, Coste O, Henke M, Suo J, Fuchs J, Angioni C, Ferreiros-Bouzas N, Geisslinger G, Scholich K

Prostaglandins Other Lipid Mediat. 2012 Jun 23.

PMID: 22732087.

Abstract

MicroRNA-124 as a novel treatment for persistent hyperalgesia.

Willemen HLDM, Huo X-J, Mao-Ying Q-L, Zijlstra J, Heijnen CJ, Kavelaars A

J Neuroinflammation. 2012 Jun 25; 9(1):143.

PMID: 22731384.

Abstract

Antinociceptive effects of intrathecal landiolol injection in a rat formalin pain model.

Mizobuchi S, Matsuoka Y, Obata N, Kaku R, Itano Y, Tomotsuka N, Taniguchi A, Nishie H, Kanzaki H, Ouchida M, Morita K

Acta Med Okayama. 2012 Jun; 66(3):285-9.

PMID: 22729110.

Abstract

Pregabalin for the treatment of fibromyalgia.

Smith MT, Moore BJ

Expert Opin Pharmacother. 2012 Jul; 13(10):1527-33.

PMID: 22725707.

Abstract

Melanocortin 4 Receptor Mediates Neuropathic Pain Through p38MAPK in Spinal Cord.

Chu H, Xia J, Xu H, Yang Z, Gao J, Liu S

Can J Neurol Sci. 2012 Jul; 39(4):458-64.

PMID: 22728852.

Abstract

Targeting voltage-gated calcium channels: developments in peptide and small molecule inhibitors for the treatment of neuropathic pain.

Vink S, Alewood PF

Br J Pharmacol. 2012 Jun 22.

PMID: 22725651.

Abstract

Sensory neurons, ion channels, inflammation and the onset of neuropathic pain.

Stemkowski PL, Smith PA

Can J Neurol Sci. 2012 Jul; 39(4):416-35.

PMID: 22728849.

Abstract

Neuropathic pain: redundant pathways, inadequate therapy.

Zochodne D

Can J Neurol Sci. 2012 Jul; 39(4):409-10.

PMID: 22728845.

Abstract

Antioxidant supplementation reduces endometriosis-related pelvic pain in humans.

Santanam N, Kavtaradze N, Murphy A, Dominguez C, Parthasarathy S

Transl Res. 2012 May 31.

PMID: 22728166.

Abstract

Persistent inflammation increases GABA-induced depolarization of rat cutaneous dorsal root ganglion neurons in vitro.

Zhu Y, Lu S, Gold MS

Neuroscience. 2012 Jun 19.

PMID: 22728089.

Abstract

The anatomy of osteoarthritic joint pain.

Witt KL, Vilensky JA

Clin Anat. 2012 Jun 21.

PMID: 22730047.

Abstract

Investigation of neuropathic pain in treated leprosy patients in Ethiopia: A cross-sectional study.

Haroun OMO, Hietaharju A, Bizuneh E, Tesfaye F, Brandsma WJ, Haanpää M, Rice ASC, Lockwood DNJ

Pain. 2012 Jun 22.

PMID: 22727538.

Abstract

The Immunomodulatory Effect of Pregabalin on Spleen Cells in Neuropathic Mice.

Jang Y, Song H-K, Yeom M Y, Jeong D C

Anesth Analg. 2012 Jun 22.

PMID: 22729962.

Abstract

Understanding pre-surgical predictors of acute pain experience following hysterectomy for benign causes: Conceptual and methodological issues.

Pinto PR, McIntyre T, Almeida A, Araújo-Soares V

Pain. 2012 Jun 22.

PMID: 22727537.

Abstract

Widespread pain hypersensitivity and facilitated temporal summation of deep tissue pain in whiplash associated disorder: An explorative study of women.

Lemming D, Graven-Nielsen T, Sörensen J, Arendt-Nielsen L, Gerdle B

J Rehabil Med. 2012 Jun 25; 44(8):648-57.

PMID: 22729792.

Abstract

ANTAGONISM OF SUPRASPINAL HISTAMINE H3 RECEPTORS MODULATES SPINAL NEURONAL ACTIVITY IN NEUROPATHIC RATS.

McGaraughty S, Chu KL, Cowart MD, Brioni JD

J Pharmacol Exp Ther. 2012 Jun 22.

PMID: 22729221.

Abstract

Sphygmomanometry-Evoked Allodynia in Chronic Pain Patients With and Without Fibromyalgia.

Chandran AB, Coon CD, Martin SA, McLeod LD, Coles TM, Arnold LM

Nurs Res. 2012 Jun 21.

PMID: 22729143.

Abstract

Acupuncture as an adjunctive therapy to pharmacological treatment in patients with chronic pain due to osteoarthritis of the knee: a 3-armed, randomized, placebo-controlled trial.

Mavrommatis CI, Argyra E, Vadalouka A, Vasilakos DG

Pain. 2012 Jun 20.

PMID: 22727499.

Abstract

Partial nerve injury induces electrophysiological changes in conducting (uninjured) nociceptive and nonnociceptive DRG neurons: Possible relationships to aspects of peripheral neuropathic pain and paresthesias.

Djouhri L, Fang X, Koutsikou S, Lawson SN

Pain. 2012 Jun 19.

PMID: 22721911.

Abstract

Functional abdominal pain patient subtypes in childhood predict functional gastrointestinal disorders with chronic pain and psychiatric comorbidities in adolescence and adulthood.

Walker LS, Sherman AL, Bruehl S, Garber J, Smith CA

Pain. 2012 Jun 19.

PMID: 22721910.

Abstract

The role of transient receptor potential ankyrin 1 (TRPA1) receptor activation in hydrogen-sulphide-induced CGRP-release and vasodilation.

Pozsgai G, Hajna Z, Bagoly T, Boros M, Kemény A, Materazzi S, Nassini R, Helyes Z, Szolcsányi J, Pintér E

Eur J Pharmacol. 2012 Jun 18.

PMID: 22721614.

Abstract

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.

Quick K, Zhao J, Eijkelkamp N, Linley JE, Rugiero F, Cox JJ, Raouf R, Gringhuis M, Sexton JE, Abramowitz J, Taylor R, Forge A, Ashmore J, Kirkwood N, Kros CJ, Richardson GP, Freichel M, Flockerzi V, Birnbaumer L, Wood JN

Open Biol. 2012 May; 2(5):120068.

PMID: 22724068.

Abstract

Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain.

Zhang Z-J, Dong Y-L, Lu Y, Cao S, Zhao Z-Q, Gao Y-J

J Neuroinflammation. 2012 Jun 21; 9(1):136.

PMID: 22721162.

Abstract

Pretreatment with intrathecal amitriptyline potentiates anti-hyperalgesic effects of post-injury intra-peritoneal amitriptyline following spinal nerve ligation.

Cheng K-I, Wang H-C, Chang L-L, Wang F-Y, Lai C-S, Chou C-W, Tsai H-P, Kwan A-L

BMC Neurol. 2012 Jun 21; 12(1):44.

PMID: 22720761.